Recombination Events Shape the Genomic Evolution of Infectious Bronchitis Virus in Europe

Infectious bronchitis of chicken is a high morbidity and mortality viral disease affecting the poultry industry worldwide; therefore, better understanding this pathogen utmost importance. The primary aim study was to obtain deeper insight into genomic diversity field infectious virus (IBV) strains using phylogenetic recombination analysis. We sequenced genome 20 randomly selected from seven European countries. After sequencing, we created sequence data set that contained 36 origin isolates 33 vaccine strains. When analyzing these 69 IBV sequences, identified 215 events highlighting some had multiple breaking points. Recombination hot spots were mostly in regions coding for non-structural proteins, nsp2, nsp3, nsp8, nsp12 regions. occurred among different genotypes involved both Ninety percent nearly half showed evidence recombination. Despite low number scattered geographical temporal whole-genome collected Gammacoronaviruses, underlines importance as major evolutionary mechanism IBVs.